Analgesics used in orthopedic Although MMA has become the A PROSPECTIVE OBSERVATIONAL DRUG UTILIZATIONAL STUDY OF ANALGESIC USE AMONG POSTOPERATIVE ORTHOPAEDIC PATIENTS IN TERTIARY CARE INSTITUTE Received : 21/03/2023 Received in revised form : 29/04/2023 Accepted : 11/05/2023 Mar 20, 2020 · Objectives Provide a comprehensive overview of pain management in the orthopedic patient population. This review aims to discuss novel analgesics and the evidence of efficacy in orthopedic surgery. Jun 7, 2024 · Background Multimodal analgesia (MMA) combines opioids with nonopioid analgesics (NOAs) to mitigate opioid-related adverse events and development of opioid use disorders. Analgesic approaches have changed in recent years in part due to patient expectations, the shift toward ambulatory surgery, and shorter hospital stays. 4103/0253 Results: Total analgesics prescribed were 1168, 117, and 369 in orthopedic, general surgery, and plastic surgery departments, respectively, and were maximum in the intraoperative period. Metamizole is a non-opioid analgesic that primarily works by inhibiting COX-3, commonly used in Europe Dec 1, 2016 · Evaluation of analgesics use in orthopedic department at tertiary care hospital in Bareilly, Uttar Pradesh, India December 2016 International Journal of Basic & Clinical Pharmacology 5 (6):2538-2541 Nov 13, 2023 · The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. May 24, 2025 · This chapter explores the current pain management strategies available for one of the most painful procedures: orthopedic fracture surgery. Patient-controlled analgesia (PCA) is a widely utilized method for managing acute and postoperative pain, allowing patients to self-administer predetermined doses of analgesics. Sep 15, 2024 · antibiotics and analgesics in an orthopaedic speciality teaching hospital. These procedures often require extensive postoperative analgesia, inc… Opioids have been traditionally used for analgesia after orthopedic trauma because of concern that nonsteroidal anti-inflammatory drug (NSAID) use increases fracture nonunion. May 30, 2019 · Results: Total analgesics prescribed were 1168, 117, and 369 in orthopedic, general surgery, and plastic surgery departments, respectively, and were maximum in the intraoperative period. Nov 18, 2024 · When multiple analgesic or anesthetic regimens were used for different orthopedic surgeries in a single article, the articles were scored by taking the average points of different regimens. It is Jul 1, 2016 · Prescribing pattern of analgesics in orthopedic in-patient department at tertiary care hospital in Guwahati, Assam, Northeast India Dwijen Kumar Choudhury, Babul Kumar Bezbaruah DOI:10. Key components of multimodal analgesia in orthopaedics include. First, there is a notable absence of data regarding inpatient analgesic use, a limitation of the dataset used. Nonsteroidal anti-inflammatory drugs (NSAIDs) are arguably the most frequently used medications in orthopedics. 3% preferred piroxicam for the same duration. Sep 1, 2025 · Hip and knee arthroplasty are a fundamental part of modern orthopaedic practice. Further, analgesic options have increased with new drugs and modes of delivery. There are a variety of analgesic and sedative strategies to provide patient comfort during reduction. When it comes to pain management in orthopedics, the use of non-steroidal anti-inflammatory drugs (NSAIDs) is very prevalent. Your doctor may use a combination of medications to improve pain relief and to minimize the need for opioids. Multimodal analgesia has become a preferred method of pain management in orthopedic practice. Although MMA has become the standard for orthopedic perioperative pain management, Sep 30, 2022 · Background: Orthopedic surgery typically results in moderate to severe pain in a majority of patients. List of references Sampognaro G, Harrell R. Medications are often prescribed for short-term pain relief after surgery or an injury. Feb 10, 2025 · Orthopedic joint replacement procedures, including total hip and knee arthroplasty, stand as vital interventions for managing degenerative joint diseases, ultimately improving patients’ quality of life [ 1 ]. NSAIDs are often the first line of treatment for mild to moderate acute musculoskeletal pain. The study’s findings are constrained by two primary limitations. Dec 16, 2024 · Opioid analgesics are often required in the postoperative period as part of multimodal analgesic therapy in many types of major orthopedic surgery (especially in total hip/knee replacement and major fractures). Postoperative pain management is critical for optimal care of orthopedic surgery patients. 2010, 1:97-108. Metamizole is a non-opioid analgesic that primarily works by inhibiting COX-3, commonly used in Europe and South America, but banned in the U. Opioids were traditionally the primary medication to target mechanisms of pain transmission. Multimodal analgesia involves the use of multiple nonopioid analgesic agents targeting different pain pathways to improve analgesia, reduce opioid consumption, and improve functional recovery. While efficacious analgesics, opiates have rapid tolerance and addictive potential. Postoperative pain control is critical in orthopedic surgery. Adjunctive therapy and preemptive analgesia such as nerve blocks, and methods of deliv … The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. Emphasis is placed on their mechanisms of action, efficacy profiles, and potential adverse effects. Multimodal Postoperative Pain Control After Orthopaedic Surgery. While opioids have traditionally been used, concerns over side effects and addiction have prompted a shift toward non-opioid and multimodal analgesic approaches. Some of the improvement in management of The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. This approach aims to optimize pain relief while minimizing opioid consumption and its associated side effects. Evidence-based Multimodal analgesia (MMA) combines opioids with nonopioid analgesics (NOAs) to mitigate opioid‐related adverse events and development of opioid use disorders. Many types of medicines are available to help manage pain, including opioids and non-steroidal anti-inflammatory drugs (NSAIDs). Utilizing more than one mode to address post-surgical pain by recruiting multiple receptors through Background and Objective: Total knee arthroplasty (TKA) is one of the most painful procedures and perioperative pain usually requires the use of many analgesics to relieve it. Aug 9, 2024 · Additionally, non-opioid analgesics might alleviate some of the early warning signs of opioid toxicity, leading to continued use despite development of adverse events. The prescriptions were analyzed and categorized into varieties based on antibiotics and analgesics prescribed, demographic parameters, comorbid conditions, type of orthopedic diseases diagnosed, polypharmacy etc. Systemic analgesics, including 2 days ago · Abstract Background: Effective postoperative pain management is vital in orthopaedic practice to enhance recovery, minimize complications, and improve patient satisfaction. Aug 27, 2024 · Introduction. The appropriate use of analgesics to relieve patient pain is an important issue of TKA. Describe multimodal analgesic techniques that help minimize the reliance on opioids in the immediate postoperative period. Jan 5, 2012 · Acute pain after orthopedic surgery should be anticipated and its treatment should be a part of every anesthetic plan. StatPearls Publishing, Treasure Island, FL; 2023. Discuss the novel formation of the recuperative and Jun 14, 2025 · Analgesics are a cornerstone medications primarily used to relieve pain without affecting its underlying cause. Most commonly used analgesic in the preoperative and postoperative period was paracetamol and that in intraoperative period was fentanyl. Regular educational interventions to improve prescribing practices among physicians at different levels may further promote rational prescribing. However, large meta-analyses have not shown The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. To characterize the drug utilization for pain management during perioperative period of TKA in China using real-world data of The percentages of analgesics prescribing from NLEM and the use of analgesic by generic name were found satisfactory. Previous research has demonstrated that multimodal analgesia reduces the use of analgesics in the early postoperative period for orthopedic procedures. Gupta A, Kaur K, Sharma S, Goyal S, Arora S, Murthy RS. May 7, 2020 · There are limited observational prescription pattern studies of analgesics in perioperative period in tertiary care hospitals for which this study was carried out in orthopedic, general surgery Abstract Background: Orthopedic surgery typically results in moderate to severe pain in a majority of patients. Results: Total analgesics prescribed were 1168, 117, and 369 in orthopedic, general surgery, and plastic surgery departments, respectively, and were maximum in the intraoperative period. . By understanding the principles of analgesic therapy, different classes of analgesics, and best practices for their use, healthcare providers can optimize pain management and minimize risks. Opioids, administered intramuscularly, as epidurals, or IV as patient-controlled analgesia, are effective for severe pain. This challenge is further complicated by scientific literature that inconsistently reports the use of anesthetics and analgesics during experimental procedures. Provide support for the use of regional anesthesia and analgesia and describe newer motor-sparing nerve blocks. Sep 30, 2021 · This study aimed to assess the intensity of pain in the post-operative patients undergoing orthopedic surgery and to evaluate the adequacy of the analgesics used. The percentages of analgesics prescribing from NLEM and the use of analgesic by generic name were found satisfactory. Jun 14, 2025 · Discover the ultimate guide to analgesics in orthopedic pharmacology, covering types, uses, and best practices for effective pain management. S. The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. Dec 22, 2024 · This article highlights the different types of pain medications commonly used in orthopedic care. The aim of this study is to evaluate the prescribing pattern of analgesics and analyze the rational use of analgesic in orthopedic in-patient department of tertiary care teaching hospital, Guwahati, Assam. Jun 14, 2025 · Conclusion Analgesics play a vital role in orthopedic pharmacology, providing relief from pain and improving the quality of life for patients. They are a cornerstone in orthopedic pain management, offering various options for different pain severities and types. Although MMA has become the standard for orthopedic perioperative pain management, guidance is less clear for the approximately 15% of patients who go on to require inpatient orthopedic rehabilitation (IOR The treatment varieties analyzed included drug therapy, considering the drugs, their pharmaceutical presentations and the route of administration most frequently used in orthopedics; and acupuncture, which has proven to be effective in special cases. Orthopaedic ERAS protocols emphasise a multimodal approach to pain management, advocating for a reduction in opioid reliance. Jun 6, 2023 · Orthopedic injuries are commonly managed in the emergency department (ED) setting. Fractures and dislocations may require reduction for proper management. Nov 13, 2023 · The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. 21 In this review, we summarize the scientific literature available to provide recommendations for integrating analgesia into rat and mouse orthopedic and wound healing models. The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. due to concerns about agranulocytosis risk. Alternative analgesic strategies, such as regional nerve blocks and non-opioid medications, are integrated into these protocols. Because opioid Abstract Background: Multimodal analgesia (MMA) combines opioids with nonopioid analgesics (NOAs) to mitigate opioid-related adverse events and development of opioid use disorders. The commonly utilized analgesic modalities are stratified into systemic and regional analgesia. J Adv Pharm Technol Res. Jun 23, 2023 · By introducing effective analgesic treatments and interventions, this procedure reduces the use of perioperative opioids and, over time, the risk of opioid toxicity and addiction. Method s: Observational research was conducted retrospectively over a month from the Medical Record department. An observational and cross-sectional study Nov 13, 2023 · Download Citation | On Nov 13, 2023, Sachin Goel and others published A Comprehensive Review of Postoperative Analgesics Used in Orthopedic Practice | Find, read and cite all the research you need The review systematically explores the pharmacological landscape of analgesics commonly used in orthopedic settings, including opioids, non-steroidal anti-inflammatory drugs, acetaminophen, and adjuvant medications. Current evidence is against the preoperative use of opioids as a single analgesic. Feb 18, 2025 · This article will delve into the different classes of drugs that orthopedic doctors commonly use to treat their patients. Abebe MM, Arefayne NR, Temesgen MM, Admass BA. Clinical aspects of acute post-operative pain management & its assessment. Utilizing more than one mode to address post-surgical pain by recruiting multiple receptors Analgesic use in orthopedic surgery across India In the context of monotherapy for acute low back pain (ALBP), 68% of orthopedicians preferred using etoricoxib for less than a week, while 40. Conclusion: The study presented the prescription trends of antibiotics and analgesics in orthopaedic department. Multimodal analgesia, which involves the use of multiple analgesic agents with different mechanisms of action, has gained prominence in postoperative pain management. Sep 13, 2025 · Multimodal analgesia has emerged as the standard of care in orthopedic surgery. rmk deke fxva ysinh sija yjxax yrjhrlym nxhovo erhlejwf ptzlyzq hdvgh iel jlmxf ivxz uqmyyorg